designit: Blocking and Randomization for Experimental Design

Intelligently assign samples to batches in order to reduce batch effects. Batch effects can have a significant impact on data analysis, especially when the assignment of samples to batches coincides with the contrast groups being studied. By defining a batch container and a scoring function that reflects the contrasts, this package allows users to assign samples in a way that minimizes the potential impact of batch effects on the comparison of interest. Among other functionality, we provide an implementation for OSAT score by Yan et al. (2012, <doi:10.1186/1471-2164-13-689>).

Version:	0.5.0
Depends:	R (≥ 4.1.0)
Imports:	rlang (≥ 0.4.0), dplyr (≥ 1.0.0), purrr, ggplot2, scales, tibble, tidyr, assertthat, stringr, R6, data.table, stats
Suggests:	testthat, roxygen2, pkgdown, knitr, markdown, rmarkdown, gt, bench, OSAT, tidyverse, printr, devtools (≥ 2.0.0), ggpattern, cowplot, bestNormalize, here
Published:	2024-03-21
DOI:	10.32614/CRAN.package.designit
Author:	Iakov I. Davydov [aut, cre, cph], Juliane Siebourg-Polster [aut, cph], Guido Steiner [aut, cph], Konrad Rudolph [ctb], Jitao David Zhang [aut, cph], Balazs Banfai [aut, cph], F. Hoffman-La Roche [cph, fnd]
Maintainer:	Iakov I. Davydov <iakov.davydov at roche.com>
BugReports:	https://github.com/BEDApub/designit/issues
License:	MIT + file LICENSE
URL:	https://bedapub.github.io/designit/, https://github.com/BEDApub/designit/
NeedsCompilation:	no
Materials:	README NEWS
CRAN checks:	designit results

Documentation:

Reference manual:	designit.pdf
Vignettes:	Basic example Using custom shuffle schedule In-vivo study design designit: a flexible engine to generate experiment layouts Nested dimension example Optimizer examples OSAT and scoring functions Plate layouts Shuffling with constraints

Downloads:

Package source:	designit_0.5.0.tar.gz
Windows binaries:	r-devel: designit_0.5.0.zip, r-release: designit_0.5.0.zip, r-oldrel: designit_0.5.0.zip
macOS binaries:	r-release (arm64): designit_0.5.0.tgz, r-oldrel (arm64): designit_0.5.0.tgz, r-release (x86_64): designit_0.5.0.tgz, r-oldrel (x86_64): designit_0.5.0.tgz

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